What should I have accomplished by 45?

See what remarkable builders and entrepreneurs achieved at age 45

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percentile
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Ahead

Notable Achievements at Age 45

Christiaan Barnard

Performed first human-to-human heart transplant

Performed the world's first successful human-to-human orthotopic heart transplant at Groote Schuur Hospital; recipient Louis Washkansky temporarily recovered.

1967
100% confidence
Source
Thurgood Marshall

Brown v. Board of Education decision (landmark victory)

Supreme Court issued unanimous opinion (Chief Justice Earl Warren) declaring 'separate but equal' unconstitutional in public education; Marshall's most famous legal victory.

1954
100% confidence
Source
Stacey Abrams

Delivered 2019 State of the Union response

Gave the official Democratic response to President Trump's State of the Union address (broadcast Feb 5, 2019).

2019
99% confidence
Source
Stacey Abrams

Selected to deliver Democratic response to State of the Union

Senate Minority Leader Chuck Schumer announced Abrams would deliver the response to the State of the Union on February 5, 2019; she became the first African-American woman to deliver the SOTU response.

2019
99% confidence
Source
Shinya Yamanaka

Kyoto University founds Center for iPS Cell Research and Applications (CiRA); Yamanaka appointed Director

In January 2008 Kyoto University established CiRA, the world's first organization solely focusing on iPS cell technology; Yamanaka named Director.

2008
99% confidence
Source
Barack Obama

Announced candidacy for President

Formally announced his candidacy for the Democratic nomination for president on February 10, 2007.

2007
99% confidence
Source
Werner Vogels

Awarded Ph.D. in Computer Science (Vrije Universiteit)

Completed Ph.D. thesis titled 'Scalable Cluster Technologies for Mission Critical Enterprise Computing' under Henri Bal and Andy Tanenbaum.

2003
99% confidence
Source
Jerry Seinfeld

Married Jessica Sklar (Jessica Seinfeld)

Married public relations executive Jessica Sklar on December 25, 1999; later had three children.

1999
99% confidence
Source
Jack Bogle

Founded The Vanguard Group

Founded The Vanguard Group (1974), pioneering a unique mutual ownership structure where fund shareholders effectively own the funds that own the firm.

1974
99% confidence
Source
Benny Hill

Film role: The Italian Job

Appeared in The Italian Job (1969) as Professor Peach (supporting feature role).

1969
99% confidence
Source
Christiaan Barnard

Death of transplant recipient Louis Washkansky

Washkansky died 18 days after transplant from pneumonia, likely related to immunosuppression.

1967
99% confidence
Source
Albert Ellis

Founded Institute for Rational Living (non-profit)

Established the Institute for Rational Living in New York (later known as the Albert Ellis Institute); served as president.

1959
99% confidence
Source
Estée Lauder

Launched Youth-Dew bath oil/perfume

Introduced Youth‑Dew, a bath oil that doubled as a perfume and shifted women to using fragrance daily; immediate commercial breakthrough.

1953
99% confidence
Source
Estée Lauder

Launched Youth-Dew bath oil/perfume

Introduced Youth-Dew, a bath oil that doubled as a perfume, which revolutionized fragrance usage and mass consumer behavior.

1953
99% confidence
Source
Deng Xiaoping

Present at PRC proclamation (Beijing)

Attended the founding proclamation of the People's Republic of China on 1 October 1949.

1949
99% confidence
Source
Eleanor Roosevelt

Stock Market Crash (Great Depression begins)

New York Stock Exchange crash begins the Great Depression; Eleanor becomes increasingly engaged in relief and reform work.

1929
99% confidence
Source
Tobi Lütke

Net worth reported at US$11.1 billion (Forbes/Wikipedia summary)

Public wealth reporting (Forbes/Wikipedia summary) lists Tobias Lütke's net worth as US$11.1 billion as of February 2025.

2025
98% confidence
Source
Kumail Nanjiani

Primetime Emmy nomination for Welcome to Chippendales

Nominated for the 2023 Primetime Emmy Award for Outstanding Lead Actor in a Limited or Anthology Series or Movie for Welcome to Chippendales.

2023
98% confidence
Source
John Elkann

Nominated Knight of the Order of Merit for Labour

Awarded Knight of the Order of Merit for Labour (Cavalieri del Lavoro) in the automotive industry by President Sergio Mattarella (May 2021).

2021
98% confidence
Source
Andrew Ng

Birth of son

Second child (son) born in 2021 (announced Aug 25, 2021).

2021
98% confidence
Source

💡 What this means for you

At age 45, you're at a pivotal point where many successful entrepreneurs made their breakthrough. Whether you're building your first company or scaling an existing one, these examples show what's possible with focus and execution.

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