What should I have accomplished by 45?

See what remarkable builders and entrepreneurs achieved at age 45

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95th
percentile
Behind
Ahead

Notable Achievements at Age 45

Christiaan Barnard

Performed first human-to-human heart transplant

Performed the world's first successful human-to-human orthotopic heart transplant at Groote Schuur Hospital; recipient Louis Washkansky temporarily recovered.

1967
100% confidence
Source
Thurgood Marshall

Brown v. Board of Education decision (landmark victory)

Supreme Court issued unanimous opinion (Chief Justice Earl Warren) declaring 'separate but equal' unconstitutional in public education; Marshall's most famous legal victory.

1954
100% confidence
Source
Stacey Abrams

Delivered 2019 State of the Union response

Gave the official Democratic response to President Trump's State of the Union address (broadcast Feb 5, 2019).

2019
99% confidence
Source
Stacey Abrams

Selected to deliver Democratic response to State of the Union

Senate Minority Leader Chuck Schumer announced Abrams would deliver the response to the State of the Union on February 5, 2019; she became the first African-American woman to deliver the SOTU response.

2019
99% confidence
Source
Barack Obama

Announced candidacy for President

Formally announced his candidacy for the Democratic nomination for president on February 10, 2007.

2007
99% confidence
Source
Werner Vogels

Awarded Ph.D. in Computer Science (Vrije Universiteit)

Completed Ph.D. thesis titled 'Scalable Cluster Technologies for Mission Critical Enterprise Computing' under Henri Bal and Andy Tanenbaum.

2003
99% confidence
Source
Jerry Seinfeld

Married Jessica Sklar (Jessica Seinfeld)

Married public relations executive Jessica Sklar on December 25, 1999; later had three children.

1999
99% confidence
Source
Jack Bogle

Founded The Vanguard Group

Founded The Vanguard Group (1974), pioneering a unique mutual ownership structure where fund shareholders effectively own the funds that own the firm.

1974
99% confidence
Source
Christiaan Barnard

Death of transplant recipient Louis Washkansky

Washkansky died 18 days after transplant from pneumonia, likely related to immunosuppression.

1967
99% confidence
Source
Estée Lauder

Launched Youth-Dew bath oil/perfume

Introduced Youth‑Dew, a bath oil that doubled as a perfume and shifted women to using fragrance daily; immediate commercial breakthrough.

1953
99% confidence
Source
Tobi Lütke

Net worth reported at US$11.1 billion (Forbes/Wikipedia summary)

Public wealth reporting (Forbes/Wikipedia summary) lists Tobias Lütke's net worth as US$11.1 billion as of February 2025.

2025
98% confidence
Source
Kumail Nanjiani

Primetime Emmy nomination for Welcome to Chippendales

Nominated for the 2023 Primetime Emmy Award for Outstanding Lead Actor in a Limited or Anthology Series or Movie for Welcome to Chippendales.

2023
98% confidence
Source
Bozoma Saint John

Departed Netflix as Chief Marketing Officer

She left the CMO role at Netflix in March 2022 (press reported her departure March 3, 2022).

2022
98% confidence
Source
Chris Murphy

Re-elected to U.S. Senate (2nd term)

Won 2018 U.S. Senate election with 825,579 votes (59.53%).

2018
98% confidence
Source
Jess Douglas

Retired from 24-hour racing; full-time cycling coach

By August 2018 she had retired from 24-hour solo racing, was working as a full-time cycling coach, had been living in Geelong for ~3 years and was about to become a grandmother.

2018
98% confidence
Source
Beto O'Rourke

Won Democratic primary for U.S. Senate

Became the Democratic nominee on March 6, 2018 with 61.8% of the primary vote.

2018
98% confidence
Source
Joel McHale

The Great Indoors canceled by CBS

CBS canceled The Great Indoors due to low ratings after one season.

2017
98% confidence
Source
Gretchen Whitmer

Term as Ingham County Prosecutor ended

Completed six-month appointment; term expired Dec 31, 2016.

2016
98% confidence
Source
Tig Notaro

Twin sons born

Tig and Stephanie welcomed twin sons (Max and Finn) in 2016 via a surrogate using Allynne's eggs; publicized in June 2016.

2016
98% confidence
Source
Ellen Pao

Resigned as CEO of Reddit

On July 10, 2015 Ellen Pao resigned from Reddit 'by mutual agreement' and was replaced by co‑founder Steve Huffman.

2015
98% confidence
Source

💡 What this means for you

At age 45, you're at a pivotal point where many successful entrepreneurs made their breakthrough. Whether you're building your first company or scaling an existing one, these examples show what's possible with focus and execution.

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